A structural gene mutation in Salmonella typhimurium resulting in repressibility of adenylosuccinase.
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چکیده
منابع مشابه
GENERATION OF A GENE CONSTRUCT TO SIPA GENE DELETION OF SALMONELLA TYPHIMURIUM
Background & Aims: Salmonella Typhimurium is a negative-gram, non-spore, free capsule, moving bacteria with Trish Perry flagella. Salmonella is the most common cause of food poisoning. The ability to enter and survive in host cells is the condition for pathogenic Salmonella species. Proteins of invasive Salmonella are transferred to the host cells by bacteria. This study was performed for gener...
متن کاملNature of the hisD3018 frameshift mutation in Salmonella typhimurium.
Histidinol dehydrogenase from three differing revertants of ICR-191A-induced frameshift hisD3018 has been purified and examined for amino acid replacements. The enzyme from one spontaneously arising revertant, R7, contains an extra proline residue, whereas that from another, R5, contains an extensive frameshifted sequence, four amino acid residues of which have been identified to date. The amin...
متن کاملLocation of a mutator gene in Salmonella typhimurium by cotransduction.
Kirchner, Carl E. J. (Suffolk County Community College, Selden, N.Y.), and Matthew J. Rudden. Location of a mutator gene in Salmonella typhimurium by cotransduction. J. Bacteriol. 92:1453-1456. 1966.-The LT7 strain of Salmonella typhimurium has been shown to possess a mutator gene which is responsible for an increase in mutation frequency for most loci tested. Preliminary results suggested the ...
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Mutants of Salmonella typhimurium, resistant to 1,2,4triazole and mapping in the trzA and trzB loci, have been found to have low to virtually absent levels of 0-acetylserine sulfhydrylase activity while remaining prototrophic for cysteine. Kinetic, chemical, and immunochemical studies of the highly purified enzymes from two trzA mutants prove that both strains bear mutant alleles for 0-acetylse...
متن کاملMutation in the crp gene of Salmonella typhimurium which interferes with inducer exclusion.
A mutation in the crp gene of Salmonella typhimurium is described which overcame the defects of ptsHI deletion mutants for growth on a number of nonphosphotransferase system compounds. This mutation abolished inducer exclusion in a leaky ptsI mutant. The possible implications for the mechanism of inducer exclusion are discussed.
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 1965
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.54.4.1254